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Paper Details

Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease.
Neurology
10
2021
APOE, APOE 4, ARIA, Alzheimer Disease, CMHs, Cerebral Microhemorrhages, DIAD, H, cerebral microbleeds, cerebral microhemorrhages, clinical, cognitive, and motor impairments, dementia, hemorrhagic amyloid-related imaging abnormality, participants, white matter lesions
Author NameAffiliation
Clifford R JackWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
Eric McDadeWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
Beau M AncesWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
Stephen CorreiaWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
Martin R FarlowWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
Neill R Graff-RadfordWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
Keith A JohnsonWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
Stephen SallowayWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
Andrew J SaykinWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
Andrew J SaykinWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
Peter R SchofieldWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
John C MorrisWashington University School of Medicine, MO Banner Alzheimers Institute (Y.S.), Instituto de Investigaciones Neurologicas Fleni, Argentina Departments of Neurology and Clinical and Translational Science (S.B.B.), University of Pittsburgh School of Medicine, Taub Institute for Research on Alzheimers Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, University of New South Wales (W.S.B.), Australia Dementia Research Centre and UK Dementia Research Institute (D.M.C., UCL Queen Square Institute of Neurology, Massachusetts General Hospital, Keck School of Medicine of USC, Butler Hospital, Brown University Alpert Medical School, RI Center for Neuroimaging, and Indiana Alzheimers Disease Research Center (A.J.S.), Indiana University School of Medicine, Royal Prince Alfred Hospital, University of Sydney, Mayo Clinic, FL German Center for Neurodegenerative Diseases (DZNE) (C.L., Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy (C.L.), University of Tubingen Department of Neurology (J.L., Ludwig-Maximilians-Universitat Munchen Munich Cluster for Systems Neurology (SyNergy) (J.L., Germany Florey Institute and The University of Melbourne (C.L.M.), Columbia University Irving Medical Center, University of Melbourne, Australia Clinical Research Center for Dementia (H.S.), Osaka City University Department of Neurology (M.S.), Hirosaki University Graduate School of Medicine and Department of Neurology (K.S.), The University of Tokyo
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