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Paper Details

Lymphocyte-driven regional immunopathology in pneumonitis caused by impaired central immune tolerance.
Sci Transl Med
46
2019
AIRE, AIRE deficiency, AIRE mutations, APECED, APECED pneumonitis, Aire, Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, BPIFB1, KCNRG, Pneumonitis, RAG, RAG deficiency, T, T and B lymphocyte, T and B lymphocytes, activated neutrophils, autoimmune diseases, c.967_979del13 AIRE mutation, death, endocrine organ failure, hypoxemic respiratory failure, impaired central immune tolerance, lung disease, lymphocytic infiltration, mice, monogenic disorder, patients, pneumonitis, pulmonary autoimmunity, radiographic and pulmonary function abnormalities, respiratory symptoms, thymoma
Author NameAffiliation
Michael Allg??uerCenter for Cancer Research
Michael Allg??uerInstitute of Pathology, University Hospital Heidelberg
Jean K LimIcahn School of Medicine at Mount Sinai
Douglas B KuhnsFrederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc.
Theo HellerNational Institute of Diabetes and Digestive and Kidney Diseases
Theo HellerNational Institute of Diabetes and Digestive and Kidney Diseases
Arun RajanCenter for Cancer Research
Arun RajanCenter for Cancer Research
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