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Paper Details

NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function.
Cancer Discov
59
2014
-JARID1A, -PHF23 (NP23) fusion, AML, H3K4me3, H3K4me3 residues, H3K4me3 sites, Hoxa, Hoxa, Hoxb, and Meis1 genes, Hoxb, JARID1A, Meis1, Meis1 genes, NJL, NP23, NP23 cells, NP23 protein, NP23-expressing myeloblasts, NUP98, PHD, PHD histone reader, PHD motifs, PHF23, acute myeloid leukemia, chromatin, disulfiram, fusion gene, humans, leukemias, leukemic, mice, mouse, myeloid, erythroid, T-cell, and B-cell leukemia, oncogenic PHD proteins, plant homeodomain, stem cell

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