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Paper Details

A cullin-RING ubiquitin ligase targets exogenous α-synuclein and inhibits Lewy body-like pathology.
Sci Transl Med
22
2019
Cul1, F-box domain-containing protein, F-box protein, F-box/LRR repeat protein 5, FBXL5, Lewy, Lewy bodies, Lewy body, PD, Parkinson's disease, RING, S-phase kinase-associated protein 1, SCF, SCF ligases, SCF) family, SCFFBXL5, SCFFXBL5, SKP1, Syn, Syn fibrils, Syn monomers, cell lines, cullin, cullin-1, cultured cells, exogenous -synuclein, exogenous Syn, human, human-derived neuroblastoma cell line, mice, neuroblastoma, neurological disorder, neurological disorders, neuronal -synuclein, patients, synucleinopathies, ubiquitin, ubiquitin ligases
Author NameAffiliation
Roland RiekETH Zurich
Matthias PeterInstitute of Biochemistry, ETH Zurich
Eliezer MasliahUniversity of California
Eliezer MasliahUniversity of California
Paola PicottiInstitute of Biochemistry, ETH Zurich
Paola PicottiInstitute of Molecular Systems Biology, ETH Zurich
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