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Paper Details

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy.
Oncotarget
7
2022
- and -, - and -deficient cells, BGB-290, DNA double-strand breaks, DSBs, FH, Fumarate, Fumarate Hydratase, KDM4A/B, KG, KG-dependent dioxygenases, Krebs-cycle-deficient renal cell carcinoma, Lysine, Lysine-specific demethylase 4A/B, PARP, PARPi, PARPis, Poly ADP-ribose, Poly ADP-ribose polymerase, RCC, SDH, SDH-deficient RCC, Succinate, Succinate Dehydrogenase, TMZ, fumarate, hereditary cancer syndromes, murine, patients, poly ADP-ribose, poly ADP-ribose polymerase, renal cell carcinoma, succinate, temozolomide, tumor
Adenosine Diphosphate Ribose, Animals, Carcinoma, Renal Cell, Citric Acid Cycle, DNA, Dioxygenases, Fumarate Hydratase, Fumarates, Humans, Jumonji Domain-Containing Histone Demethylases, Kidney Neoplasms, Lysine, Mice, Poly (ADP-Ribose) Polymerase-1, Poly(ADP-ribose) Polymerase Inhibitors, Succinate Dehydrogenase, Succinates, Temozolomide
Author NameAffiliation
Daiki UenoDavid Geffen School of Medicine at university of california los angeles
Daiki Ueno
Juan C VasquezYale University School of Medicine
Juan C Vasquez
Amrita SuleYale University School of Medicine
Amrita Sule
Jiayu LiangWest China Hospital/School of Medicine
Jinny van DoornYale University School of Medicine
Ranjini K SundaramYale University School of Medicine
Sam FriedmanYale University School of Medicine
Randy CaliliwDavid Geffen School of Medicine at university of california los angeles
Shinji OhtakeDavid Geffen School of Medicine at university of california los angeles
Xun BaoKarmanos Cancer Institute, Wayne State University
Jing LiKarmanos Cancer Institute, Wayne State University
Huihui YeUniversity of California los angeles
Karla BoydYale University School of Medicine
Rong-Rong HuangUniversity of California los angeles
Jack DodsonUniversity of California los angeles
Paul C BoutrosUniversity of California los angeles
Ranjit S BindraYale University School of Medicine
Ranjit S Bindra
Brian ShuchDavid Geffen School of Medicine at university of california los angeles
Brian Shuch
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