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Paper Details

Characterization of allosteric modulators that disrupt androgen receptor co-activator protein-protein interactions to alter transactivation-Drug leads for metastatic castration resistant prostate cancer.
SLAS Discov
0
2023
AR, AR binding function 3, AR positive cell lines, AR-V7 splice variants, Androgen, Androgen Receptor, BF-3, BF-3 pockets, BP-1, C4-2 castration resistant prostate cancer (CRPC) cell line, CRPC, DHT, H-DHT, PSA, S3-11, SRC-1, TIF2, TIF2 box 3, TIF2 box 3 LXXLL, Transcriptional Intermediary Factor 2, androgen, androgen receptor co-activator, cancer, castration resistant prostate cancer, dihydrotestosterone, full length AR, hydrobenzo-oxazepins, metastatic CRPC, metastatic castration resistant prostate cancer, orthosteric ligand binding site, p160 coactivator, phenyl-methyl-indoles, prostate cancer, prostate cancer cell lines, prostate specific antigen, thiadiazol-5-piperidine-carboxamides
Author NameAffiliation
Carlos J Camachoat the University of Pittsburgh
Carlos J Camachoat the University of Pittsburgh
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Release 1.2