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Paper Details

A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue.
J Pathol
14
2020
Areg, Bmp6, CUL3, Deficiency of NRF2, E79Q, Hk2, KEAP1, KRT14, LSL-Nrf2E79Q, Myc, NFE2L2, NFE2L2 oncogene, NRF2, NRF2 E79Q protein, NRF2 protein, NRF2-activating mutations, NRF2E79Q, Ppard, RNA, Vegfa, cancer, cultured NRF2E79Q murine esophageal epithelial cells, endogenous Nfe2l2 genomic locus, human, hyperplasia of squamous cell tissues of the tongue, forestomach, and esophagus, hyperplasia of the esophagus, forestomach, and tongue, hyperplasia of the upper gastrointestinal tract, hypersensitivity to a, keratin, keratin 14, keratin 14 (KRT14)-positive murine tissues, mouse, murine, nuclear factor (erythroid-derived 2)-like 2, patients, squamous cancers, squamous cell carcinoma, squamous cell carcinomas, squamous cell carcinomas of the esophagus
Author NameAffiliation
Stephanie A MontgomeryLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine
Stephanie A MontgomeryUniversity of North Carolina
Jeremy M SimonLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine
Jeremy M SimonUniversity of North Carolina at Chapel Hill School of Medicine
Jeremy M SimonUniversity of North Carolina at Chapel Hill
David Neil HayesUniversity of Tennessee Health Science Center for Cancer Research, University of Tennessee
David Neil HayesUniversity of Tennessee Health Science Center for Cancer Research, University of Tennessee
Scott H RandellLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine
Scott H RandellUniversity of North Carolina at Chapel Hill School of Medicine
Scott H RandellBroad Institute of MIT and Harvard
Michael B MajorLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine
Michael B MajorUniversity of North Carolina at Chapel Hill School of Medicine
Michael B MajorUniversity of North Carolina at Chapel Hill School of Medicine
Michael B MajorWashington University
Michael B MajorLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine
Michael B MajorUniversity of North Carolina at Chapel Hill School of Medicine
Michael B MajorUniversity of North Carolina at Chapel Hill School of Medicine
Michael B MajorWashington University
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