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Paper Details

Pharmaceutical Interference of the EWS-FLI1-driven Transcriptome By Cotargeting H3K27ac and RNA Polymerase Activity in Ewing Sarcoma.
Mol Cancer Ther
7
2021
-, -FLI1 target genes, C, CDK7, EWS, EWSR1, Ewing Sarcoma, Ewing sarcoma, Ewing sarcoma cells, FLI1, FLI1 t(11;22)(q24;q12), FLI1-, GSK-J4, H3K27 demethylase, H3K27ac, H3K27me, PDX, PDX Ewing sarcoma cells, PDX models, RNA Polymerase, RNA polymerase II, THZ1, Transcriptome, children, enhancers, ex vivo, malignancy of the bone, patient, patients, promoters, tumors
Author NameAffiliation
Mikhail G DozmorovVirginia Commonwealth University
Cyril H BenesMassachusetts General Hospital Cancer Center
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Release 1.2