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Paper Title
Phase 1 study of the MDM2 inhibitor AMG 232 in patients with advanced P53 wild-type solid tumors or multiple myeloma.
PubMed
Paper Journal Title
Investigational New Drugs
Paper Citation Count
59
Paper Publication Year
2020
Bio Mention
AMG, AMG 232, BC, DDLPS, ER+, GBM, MDM2, MDM2-overexpressing ER, MM, OST, P53, P53 wild-type solid tumors, P53WT, TP53, WDLPS, advanced solid tumors, anemia, breast cancer, cytopenias, decreased appetite, diarrhea, fatigue, glioblastoma multiforme, human, multiple myeloma, nausea, neutropenia, p53, patients, serum macrophage inhibitor cytokine-1, solid tumors, thrombocytopenia, vomiting
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Author Name
Affiliation
David S Siegel
John Theurer Cancer Center at the Hackensack University Medical Center
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