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The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.
Nat Cell Biol
121
2015
5-hydroxymethylcytosine, 5-methylcytosine, 5hmC, ESC, ESCs, H3K56ac, H3K9ac, NANOG, OCT4, S6KO, S6KO ESCs, SIRT6, SOX2, Sirt6, TET, TET enzymes, TETs, Tet, cell lineages, chromatin, embryonic, embryonic stem cell, embryonic stem cell fate, embryonic stem cells, histone, histone H3, histone deacetylase, mice, neural genes, sirtuin 6, ten-eleven translocation enzymes
Author NameAffiliation
Lukas ChavezLa Jolla Institute for Allergy and Immunology, university of california san diego Department of Pharmacology, university of california san diego Moores Cancer Center
Lukas ChavezLa Jolla Institute for Allergy and Immunology, university of california san diego Department of Pharmacology, university of california san diego Moores Cancer Center
Cesar A SommerThe Center for Regenerative Medicine (CReM), Boston Medical Center, Boston University School of Medicine
Adrianne Gladden-YoungThe Broad Institute of Harvard and MIT
Gustavo MostoslavskyThe Center for Regenerative Medicine (CReM), Boston Medical Center, Boston University School of Medicine
Konrad Hochedlinger1] The Massachusetts General Hospital Cancer Center, Harvard Medical School, USA [2] The MGH Center for Regenerative Medicine, USA [3] Howard Hughes Medical Institute
Alon GorenThe Broad Institute of Harvard and MIT
Anjana RaoLa Jolla Institute for Allergy and Immunology, university of california san diego Department of Pharmacology, university of california san diego Moores Cancer Center
Raul Mostoslavsky1] The Massachusetts General Hospital Cancer Center, Harvard Medical School, USA [2] The MGH Center for Regenerative Medicine
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