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Paper Details

Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling.
Cancer Immunol Res
27
2021
4-1BB, CAR, CAR construct, CAR-T cells, CD28, CD3 chain, Chimeric Antigen Receptor, Chimeric antigen receptor, FWRs, Framework Regions, amino acids, mAb single-chain variable fragment, scFv
Author NameAffiliation
Gaetano FinocchiaroFondazione IRCCS Istituto Neurologico Carlo Besta
Gaetano FinocchiaroFondazione IRCCS Istituto Neurologico Carlo Besta
Brian KuhlmanLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Brian KuhlmanUniversity of North Carolina at Chapel Hill
Nikolay V DokholyanPennsylvania State University College of Medicine
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