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Paper Details

Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers.
Nat Commun
19
2023
AD, APOE, APOE4, APOE4 inhibitory neurons, APP, Alzheimer disease, MS4A, MS4A microglia, NCK2, PSEN1, SNARE, TREM2, TREM2 oligodendrocytes, amyloid, autosomal dominant Alzheimer disease, cell types, complement cascade, complement cascade genes, effector cell types, ferroptosis, genes, microglia, neurons, risk variant, risk-modifying variant, single, snRNA, variant
Author NameAffiliation
John C MorrisHope Center for Neurological Disorders, Washington University School of Medicine in St. Louis
John C MorrisKnight Alzheimer Disease Research Center, Washington University School of Medicine in St. Louis
John C MorrisWashington University School of Medicine in St. Louis
Eric McDadeWashington University School of Medicine in St. Louis
Alison M GoateRonald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai
Martin R FarlowIndiana University School of Medicine
Jonathan KipnisWashington University School of Medicine in St. Louis
Jonathan KipnisCenter for Brain Immunology and Glia (BIG), Washington University School of Medicine in St. Louis
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