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Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis.
Oncotarget
40
2016
ALDH, Akt, CCSC, CCSCs, CXCL8, LY294002, PI3K, PI3KR2, PI3KR2-overexpressing colon cancer stem cells, aldehyde, aldehyde dehydrogenase, cleaved caspase 3, colon cancer, colon cancer stem cells, cyclin D1, mTOR, mechanistic target of rapamycin, phosphoinositide 3-kinase, rapamycin, sporadic colon cancer, tumor
Author NameAffiliation
Maria-Cecilia LopezUniversity of Florida
Henry V BakerUniversity of Florida
Henry V BakerUniversity of Florida
John M KoomenH. Lee Moffitt Cancer Center and Research Institute
Jill S Barnholtz-SloanCase Comprehensive Cancer Center
Jill S Barnholtz-SloanCase Comprehensive Cancer Center
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