Skip to Main Content

Paper Details

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers.
Nat Genet
255
2015
DNA polymerase, High, High-grade bMMRD brain tumors, bMMRD, bMMRD cancers, bMMRD/polymerase-mutant cancers, biallelic mismatch repair deficiency, cancer, cancer genomes, cancer-cell, cancers, children, exonic, humans, polymerase, replication error repair genes, tumor, ultra-hypermutated cancers
Author NameAffiliation
Richard de BorjaThe Hospital for Sick Children
Ludmil B AlexandrovWellcome Trust Sanger Institute
Ludmil B AlexandrovWellcome Trust Sanger Institute
David C WedgeWellcome Trust Sanger Institute
Peter Van LooWellcome Trust Sanger Institute, University of Leuven
Patrick S TarpeyWellcome Trust Sanger Institute
Paul CouplandWellcome Trust Sanger Institute
Aaron PollettMount Sinai Hospital
Moritz GerstungWellcome Trust Sanger Institute
Manasa RamakrishnaWellcome Trust Sanger Institute
Marc RemkeThe Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
Paul C NathanThe Hospital for Sick Children, University of Toronto
Paul C NathanThe Hospital for Sick Children, University of Toronto
Steven Gallinger1] The Familial Gastrointestinal Cancer Registry at the Zane Cohen Centre for Digestive Disease, Mount Sinai Hospital
Peter B Dirks1] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
Annie Huang1] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, University of Toronto
Stephen W SchererThe Hospital for Sick Children, University of Toronto
Stephen W SchererThe Hospital for Sick Children, University of Toronto
Michael D Taylor1] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
Michael D Taylor1] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
David MalkinThe Hospital for Sick Children, University of Toronto
David MalkinThe Hospital for Sick Children, University of Toronto
Phillip A FutrealWellcome Trust Sanger Institute
Michael R StrattonWellcome Trust Sanger Institute
Eric Bouffet1] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, University of Toronto
Cynthia HawkinsUniversity of Toronto, Canada. [2] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
Cynthia HawkinsUniversity of Toronto, Canada. [2] The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
Peter J CampbellWellcome Trust Sanger Institute, University of Cambridge
Uri TaboriThe Hospital for Sick Children, Canada. [2] The Arthur and Sonia Labatt Brain Tumour Research Centre, University of Toronto
  • 1 - 29

Datasets