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Paper Details

Polycomb deficiency drives a FOXP2-high aggressive state targetable by epigenetic inhibitors.
Nat Commun
4
2023
BET, EZH2, EZH2-deficient tumors, Ezh2, Ezh2 haplo-insufficient tumors, FOXP2, H3K27 demethylase, H3K27me3, KRAS, KRAS-driven lung adenocarcinomas, PRC2, Polycomb, Polycomb Repressive Complex 2 (PRC2), Polycomb deficiency, cancer, cancers, fully-insufficient tumors, histone methyltransferase, human, lung adenocarcinomas, three-dimensional cultures
Author NameAffiliation
Robert M FlightUniversity of Kentucky
Robert M FlightMarkey Cancer Center, University of Kentucky
Stuart H OrkinBoston Children's Hospital
Hunter N B MoseleyUniversity of Kentucky
Hunter N B MoseleyMarkey Cancer Center, University of Kentucky
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