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Paper Details

Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension.
N Engl J Med
86
2023
Author NameAffiliation
Nathan I ShapiroBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Roy G BrowerBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Samuel M BrownBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Matthew C ExlineBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Michelle N GongBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Colin K GrissomBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Douglas HaydenBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Catherine L HoughBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Theodore J IwashynaBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Alan E JonesBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Akram KhanBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Kathleen D LiuBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Pauline K ParkBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Todd W RiceBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Matthew W SemlerBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Jay S SteingrubBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Daniel TalmorBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Boyd Taylor ThompsonBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Donald M YealyBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
Wesley H SelfBeth Israel Deaconess Medical Center-Harvard Medical School (N.I.S.), Massachusetts General Hospital, Beth Israel Deaconess Medical Center (D.T.), Baystate Medical Center, Denver Health Medical Center, University of Colorado School of Medicine, Johns Hopkins University School of Medicine, Intermountain Medical Center, University of Utah, C.K.G.) the Ohio State University Wexner Medical Center, Montefiore Medical Center, Oregon Health and Science University, University of Mississippi Medical Center, University of California, Medical Center, Wake Forest Baptist Medical Center, University of Michigan Medical School, Vanderbilt University Medical Center, University of Pittsburgh School of Medicine
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Datasets

ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link