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Paper Details

A human cancer cell line initiates DNA replication normally in the absence of ORC5 and ORC2 proteins.
Journal of Biological Chemistry
11
2020
AAA+ ATPase domain, Cas9, HCT116, MCM2-7, N, N terminally deleted ORC5, ORC, ORC1, ORC1-6, ORC2, ORC2 protein, ORC2 proteins, ORC3, ORC4 proteins, ORC5, ORC5 gene, ORC5 mutant cells, ORC5 protein, ORC5-depleted cells, WT cells, cancer, cancer cell lines, cancer cells, chromatin, colon cancer, double mutant cells, human, human HCT116 colon cancer cells, human cancer cell line, human cell lines, initiator ATG, methionine, minichromosome maintenance protein complex, mutant cells, origin recognition complex, origins, origins of replication, ring-shaped heterohexameric ATPase
Author NameAffiliation
Anindya DuttaUniversity of Virginia School of Medicine
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Release 1.2