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Paper Details

Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy.
JAMA Neurol
17
2023
BRAF, Drug, Drug-Resistant, Drug-resistant MTLE, Erk1/2, Hippocampal, KRAS, MAPK, MTLE, Mesial Temporal Lobe Epilepsy, Mesial temporal lobe epilepsy, Mitogen-Activated Protein Kinase, NF1, PTPN11, PTPN11 variants, Participants, Patients, Raf, Ras, SOS1, drug-resistant, epilepsy, focal cortical dysplasia, focal epilepsy, genomic region, germline genetic variants, glial cells, low-grade epilepsy-associated tumors, mesial temporal sclerosis, mitogen-activated protein kinase, patients
Author NameAffiliation
Ming-Hui ChenManton Center for Orphan Disease Research, Boston Children's Hospital
Ingrid E SchefferUniversity of Melbourne
Ingrid E Scheffer
Ingrid E SchefferUniversity of Melbourne, Royal Children's Hospital
Ingrid E SchefferFlorey Institute of Neuroscience and Mental Health
Ingrid E SchefferMurdoch Children's Research Institute
Shozeb HaiderDepartment of Pharmaceutical and Biological Chemistry, University College London School of Pharmacy
Michael S HildebrandUniversity of Melbourne
Michael S HildebrandMurdoch Children's Research Institute
Murat GunelYale University School of Medicine
Richard P LiftonYale University School of Medicine
Richard P LiftonThe Rockefeller University
Richard P LiftonYale University School of Medicine
Richard P LiftonThe Rockefeller University
Robert Mark RichardsonMassachusetts General Hospital
Sanda AlexandrescuBoston Children's Hospital, Harvard Medical School
Erin L HeinzenDivision of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill.
Erin L HeinzenUniversity of North Carolina at Chapel Hill.
Christopher A WalshManton Center for Orphan Disease Research, Boston Children's Hospital
Christopher A WalshBroad Institute of MIT and Harvard
Christopher A WalshHarvard Medical School
Christopher A WalshAllen Discovery Center for Human Brain Evolution, Boston Children's Hospital, Harvard Medical School
Christopher A WalshHoward Hughes Medical Institute
Christopher A WalshManton Center for Orphan Disease Research, Boston Children's Hospital
Christopher A WalshBroad Institute of MIT and Harvard
Christopher A WalshHarvard Medical School
Christopher A WalshAllen Discovery Center for Human Brain Evolution, Boston Children's Hospital, Harvard Medical School
Christopher A WalshHoward Hughes Medical Institute
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