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Paper Details

A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders.
PLoS ONE
22
2011
MAPK, S1P, S1P lyase, S1P receptor, Sphingosine-1-phosphate, StSPL, Symbiobacterium thermophilum, VEGF, aberrant, autoimmune diseases, blood, breast (MCF-7, cancer, carcinoma, carcinoma cells, chicken, colon (, colon (HCT 116) carcinoma cells, connective tissue growth factor, endothelial cells, fibrosis, hyperproliferative disorders, inflammation, mesangial cells, mice, prokaryotic S1P lyase, recombinant StSPL, renal mesangial cells, tumor, wild-type StSPL

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