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Paper Details

ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers.
bioRxiv
2
2023
ASCL1, ASCL1-expressing lung tumor cells, ASCL1-high NE, DUSP6, ERK, ERK1/2, ERK1/2-selective phosphatase, ETV5, MEK, NE, NE lung cancers, NE lung tumors, NE-NSCLCs, NSCLC, NSCLC-NE, NSCLCs, RNA, SCLC, SCLC/NSCLC-NE tumor cell, SCLCs, SPRED1, SPRY4, achaete-scute complex homolog 1, cancer, down-regulated genes, dual specificity phosphatase 6, genes, lineage oncogene, neuroendocrine, neuroendocrine lung cancers, neuroendocrine non-small cell lung cancers, phospho-ERK1/2, small cell lung cancers, transcription factor

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Release 1.2