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Paper Details

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.
Nat Commun
33
2021
CX-5461, RNA-POL I, TOP2B, cardiotoxicity, children, high, high-, high-risk neuroblastoma, human, leukemia, mouse, neuroblastoma, patient, patients, topoisomerase I, topoisomerase II beta, tumor
Author NameAffiliation
Madan Mohan BabuSt. Jude Children's Research Hospital
Madan Mohan BabuSt. Jude Children's Research Hospital
Shondra M Pruett-MillerSt. Jude Children's Research Hospital
Taosheng ChenSt. Jude Children's Research Hospital
Lucy A GodleyThe University of Chicago
Elizabeth StewartSt. Jude Children's Research Hospital
Elizabeth StewartSt. Jude Children's Research Hospital
Elizabeth StewartSt. Jude Children's Research Hospital
Elizabeth StewartSt. Jude Children's Research Hospital
John EastonSt. Jude Children's Research Hospital
John EastonSt. Jude Children's Research Hospital
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