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Paper Details

Removal of a genomic duplication by double-nicking CRISPR restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer.
bioRxiv
2
2023
700bp genomic duplication, ASD, DN, DN-CRISPRs, Flailer, MyoVa, MyosinVA mutant, anxiety, autism spectrum disorder, duplicate genes, gene regions, genomic duplications, genomic regions, mouse, neurodegenerative, neurodegenerative conditions, neurological and behavioral symptoms, primary cortical neurons

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