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Paper Details

An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons.
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2023
Akt, Alzheimer's disease, CRISPR, NM_, PI3K, S1038C, TTC3, TTC3 p, TTC3 p., TTC3 p.S1038C variant, actin, actin cytoskeleton, cortical neurons, genes, iPSC, iPSC-derived forebrain neurons, iPSC-derived neuronal progenitor cells, iPSCs, induced pluripotent stem cells, isogenic pair, neurons, tetratricopeptide repeat domain 3, tetratricopeptide repeat domain 3 (TTC3) gene
Author NameAffiliation
Margaret A Pericak-VanceJohn P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, USA John T. Macdonald Foundation Department of Human Genetics
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Release 1.2