Skip to Main Content

Paper Details

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease.
Nature
186
2020
Casp8, D324H, D324N, D324Y, D325A, Embryonic lethality, Mlkl, RIPK1, RIPK1 kinase, RIPK3, Ripk1-/-, Ripk1D325A, Ripk1D325A mutant, Ripk1D325A/+, Ripk1D325A/D325A, Ripk1D325A/D325A and Ripk1D325A/+ cells, Ripk3, TNF, autoinflammatory disease, caspase, caspase-8, embryonic lethality, humans, intermittent, lymphadenopathy, mice, mouse, multi-organ inflammation, periodic fever syndrome, systemic inflammation
Author NameAffiliation
Wanxia Li TsaiNational Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health
James C MullikinNational Human Genome Research Institute, National Institutes of Health
James C MullikinNational Human Genome Research Institute, National Institutes of Health
Sergio D RosenzweigClinical Center, National Institutes of Health
Massimo GadinaNational Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health
Massimo GadinaNational Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health
Daniel L KastnerNational Human Genome Research Institute, National Institutes of Health
  • 1 - 7

Datasets

Release 1.2