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Paper Details

MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability.
Nat Commun
40
2018
MAX, MYC, MYC protein, MYC target gene promoters, PNUTS, PP1, c-MYC, cancers, chromatin, proliferating cells, protein phosphatase 1, protein phosphatase-1 nuclear-targeting subunit, serine, threonine
Cell Line, Tumor, Chromatin, Chromatin Immunoprecipitation, DNA-Binding Proteins, Electrophoresis, Gel, Two-Dimensional, Humans, Immunoblotting, Immunoprecipitation, Mass Spectrometry, Nuclear Proteins, Protein Phosphatase 1, Protein Stability, Proto-Oncogene Proteins c-myc, RNA-Binding Proteins
Author NameAffiliation
Dharmendra DingarPrincess Margaret Cancer Centre, University Health Network
William B TuPrincess Margaret Cancer Centre, University Health Network
William B TuUniversity of Toronto
Diana ResetcaPrincess Margaret Cancer Centre, University Health Network
Diana ResetcaUniversity of Toronto
Corey LourencoPrincess Margaret Cancer Centre, University Health Network
Corey LourencoUniversity of Toronto
Aaliya TamachiPrincess Margaret Cancer Centre, University Health Network
Jason De MeloPrincess Margaret Cancer Centre, University Health Network
Kathleen E HoulahanUniversity of Toronto
Kathleen E HoulahanOntario Institute for Cancer Research
Manpreet KalkatPrincess Margaret Cancer Centre, University Health Network
Manpreet KalkatUniversity of Toronto
Pak-Kei ChanPrincess Margaret Cancer Centre, University Health Network
Paul C BoutrosUniversity of Toronto
Paul C BoutrosOntario Institute for Cancer Research
Paul C BoutrosUniversity of Toronto
Brian RaughtPrincess Margaret Cancer Centre, University Health Network
Brian RaughtUniversity of Toronto
Linda Z PennPrincess Margaret Cancer Centre, University Health Network
Linda Z PennUniversity of Toronto
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