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Paper Details

3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis.
Mol Cell
99
2020
3D Culture Models, Cancer, GPX4, NRF2, NRF2-hyperactivated tumors, cancer, cancer spheroid, cancer spheroid models, lipid peroxidase, lung tumor, lung tumor spheroids, mTOR, mammalian target, matrix-deprived cells, rapamycin, spheroid, spheroids, tumor
Author NameAffiliation
Steven P GygiHarvard Medical School
Steven P GygiHarvard Medical School
Joan S BruggeHarvard Medical School, USA Ludwig Cancer Center
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Release 1.2