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Paper Title
Efficacy and Safety of an Investigational Single-Course CRISPR Base-Editing Therapy Targeting in Nonhuman Primate and Mouse Models.
PubMed
Paper Journal Title
Circulation
Paper Citation Count
31
Paper Publication Year
2023
Bio Mention
ALT, AST, CRISPR, Cynomolgus monkeys, DNA base, LDL-C, LDL-cholesterol, Mouse, Primate, VERVE, VERVE-, VERVE-101, VERVE-101mu, atherosclerotic cardiovascular disease, bilirubin, blood PCSK9, blood PCSK9 protein, cholesterol, germline, heterozygous familial hypercholesterolemia, human, mice, murine, murine F1 progeny, patients, sperm, sperm samples
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Sekar Kathiresan
Amit Khera
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