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Paper Details

Efficacy and Safety of an Investigational Single-Course CRISPR Base-Editing Therapy Targeting in Nonhuman Primate and Mouse Models.
Circulation
31
2023
ALT, AST, CRISPR, Cynomolgus monkeys, DNA base, LDL-C, LDL-cholesterol, Mouse, Primate, VERVE, VERVE-, VERVE-101, VERVE-101mu, atherosclerotic cardiovascular disease, bilirubin, blood PCSK9, blood PCSK9 protein, cholesterol, germline, heterozygous familial hypercholesterolemia, human, mice, murine, murine F1 progeny, patients, sperm, sperm samples

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