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Paper Details

Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models.
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2023
2D, 2D/, 3D, 3D cell culture models, A, A42, A673T, A673T variant, AD, APP, APP A673T, APP A673T variant, APP Swedish and London mutations, Alzheimer's disease, CTF, amyloid beta (A), amyloid precursor protein, amyloid precursor protein (APP) gene, neuronal, neuronal cell, neuronal cell culture models, p62, peptides, phospho-tau, plasma, protective variant, sAPP
Author NameAffiliation
Teemu KuulasmaaInstitute of Biomedicine, University of Eastern Finland
Rudolph E TanziGenetics and Aging Research Unit, McCance Center for Brain Health, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital and Harvard Medical School
Markku LaaksoUniversity of Eastern Finland, Kuopio University Hospital
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Release 1.2