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Paper Details

DGAT2 Inhibition Potentiates Lipid Droplet Formation To Reduce Cytotoxicity in APOL1 Kidney Risk Variants.
J Am Soc Nephrol
10
2022
APOL1, APOL1 kidney organoids, APOL1 risk variants, Cas9, DGAT1, DGAT2, G0, IFN-, Kidney Risk Variants, O, RNA, apolipoprotein L1, diacylglycerol, diacylglycerol O-acyltransferases 1 and 2, fatty acid, genes, high, high-risk APOL1 kidney organoids, high-risk APOL1 organoids, human, human podocytes, human-derived APOL1 and, induced pluripotent stem cells, kidney disease, organoids, unstimulated, wild-type APOL1 organoids
Author NameAffiliation
Seth L AlperBeth Israel Deaconess Medical Center and Harvard Medical School
David J FriedmanBeth Israel Deaconess Medical Center and Harvard Medical School
Martin R PollakBeth Israel Deaconess Medical Center and Harvard Medical School
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Datasets

Release 1.2