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Paper Details

Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment.
Sci Transl Med
2
2023
(pro-opiomelanocortin) gene, -, DNA, MC4R, POMC, POMC-expressing hypothalamic neurons, WA01, epigenetic, expressing neurons, hESC, hESCs, human, human embryonic stem cell, metastable epiallele, obese, obesity
Author NameAffiliation
Elsa LeitãoInstitute of Human Genetics, University Hospital Essen
Christopher SchröderInstitute of Human Genetics, University Hospital Essen
Bernhard HorsthemkeInstitute of Human Genetics, University Hospital Essen
Karl-Heinz JöckelInstitute of Medical Informatics, University Hospital Essen
Markus M N??thenInstitute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn
Markus M N??thenInstitute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn
Per HoffmannInstitute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn
Stefan HermsInstitute of Human Genetics, School of Medicine and University Hospital Bonn, University of Bonn
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