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Paper Details

MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells.
Science
325
2016
CDKN2A, MTA, MTAP, MTAP deletions, MTAP-null cancer cell lines, PRMT5, PRMT5 arginine methyltransferase, WDR77, arginine, cancer, cancer cell, cancer cell lines, cancer cells, cancer lineages, methylthioadenosine, methylthioadenosine phosphorylase, protein arginine methyltransferase 5, tumor, tumor suppressor gene
Author NameAffiliation
Gregory V KryukovDana-Farber Cancer Institute, Harvard Medical School, USA. The Broad Institute of MIT and Harvard
Aviad TsherniakThe Broad Institute of MIT and Harvard
Aviad TsherniakThe Broad Institute of MIT and Harvard
Francisca VazquezDana-Farber Cancer Institute, Harvard Medical School, USA. The Broad Institute of MIT and Harvard
Barbara A WeirDana-Farber Cancer Institute, Harvard Medical School, USA. The Broad Institute of MIT and Harvard
Barbara A WeirDana-Farber Cancer Institute, Harvard Medical School, USA. The Broad Institute of MIT and Harvard
Glenn S CowleyThe Broad Institute of MIT and Harvard
Jesse S BoehmThe Broad Institute of MIT and Harvard
Jesse S BoehmThe Broad Institute of MIT and Harvard
David E RootThe Broad Institute of MIT and Harvard
David E RootThe Broad Institute of MIT and Harvard
Todd R GolubThe Broad Institute of MIT and Harvard
Todd R GolubThe Broad Institute of MIT and Harvard
Clary B ClishThe Broad Institute of MIT and Harvard
Clary B ClishThe Broad Institute of MIT and Harvard
James E BradnerDana-Farber Cancer Institute, Harvard Medical School, USA. The Broad Institute of MIT and Harvard
William C HahnDana-Farber Cancer Institute, Harvard Medical School, USA. The Broad Institute of MIT and Harvard
William C HahnDana-Farber Cancer Institute, Harvard Medical School, USA. The Broad Institute of MIT and Harvard
Levi A GarrawayDana-Farber Cancer Institute, Harvard Medical School, USA. The Broad Institute of MIT and Harvard
Levi A GarrawayDana-Farber Cancer Institute, Harvard Medical School, USA. The Broad Institute of MIT and Harvard
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