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Paper Details

Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1.
J Am Chem Soc
31
2022
C1113A, C1113A mutant, DCAF1, E3 ligase substrate receptor, E3 ligases, azetidine acrylamide, azetidine acrylamides, cysteine, human, human cells, ligandable sites
Author NameAffiliation
Stuart L SchreiberBroad Institute of Harvard and MIT
Stuart L SchreiberHarvard University
Stuart L SchreiberBroad Institute of Harvard and MIT
Stuart L SchreiberHarvard University
Benjamin F CravattDepartment of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute
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