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Paper Title

Central leptin gene delivery evokes persistent leptin signal transduction in young and aged-obese rats but physiological responses become attenuated over time in aged-obese rats.

Paper Journal Title

Neuropharmacology

Paper Citation Count

Paper Publication Year

2002

Bio Mention

BAT, NPY, STAT3, UCP1, age-related obese, aged-obese, brown adipose tissue, hypothalamic NPY and POMC mRNAs, leptin, leptin receptor, obese, oxygen, rat, rat leptin cDNA, rats, serum leptin

Mesh Descriptor

Adipose Tissue, Brown, Aging, Animals, Body Weight, DNA, Complementary, Drug Delivery Systems, Eating, Genetic Therapy, Genetic Vectors, Injections, Intraventricular, Leptin, Male, Obesity, Oxygen Consumption, Rats, Rats, Inbred BN, Rats, Inbred F344, Signal Transduction

Author Name	Affiliation
Philip J Scarpace	Education and Clinical Center, Department of Veterans Affairs Medical Center

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