CD3, CD4, CD4+, CD4+ T cell, CD8, CD8 T cells, CD8+, CD8+ T cell, CD8+ TEMRA population, CD8+ and CD4+ T cells, CD8+ and CD4+ populations, CD8+ effector memory cells, CTLA4, Differentially expressed genes, Foralumab, HLA-DP, HLA-DQ, IFNg, IL-17, KIR3DL2, KLRG1, LAP, OKT3, T cell, T cells, TGF-B1, TGFB, TGFB1, TIGIT, TNFa, Teplizumab, UCHT1 anti-human CD3 mAb, anti-CD3 Mab, anti-CD3 monoclonal antibody, autoimmune and CNS diseases, autoimmune diseases, central nervous system (CNS) inflammation, diabetes, genes, granzyme B, human, humanized, humanized anti-CD3 Mab, humans, memory CD4+ population, monocytes, mouse, naive CD8+ and CD4+ T cells, nasal anti-CD3 Mab, nave CD4+, perforin, scRNAseq, transplant rejection