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Paper Details

Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake.
Sci Signal
22
2016
AgRP, BigLEN, GPCR, GPR171, MS0015203, agouti-related protein, b-LEN, family A GPCRs, food-related disorders, heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptor, mice, neuropeptide Y, neuropeptide receptor GPR171, proSAAS, shRNA, short hairpin RNA
Author NameAffiliation
Ivone GomesIcahn School of Medicine at Mount Sinai
Paola BisignanoIcahn School of Medicine at Mount Sinai
Achla GuptaIcahn School of Medicine at Mount Sinai
Mihaly MezeiIcahn School of Medicine at Mount Sinai
Lakshmi A DeviIcahn School of Medicine at Mount Sinai
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