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Paper Details

Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease.
Nat Commun
23
2021
27 genes, Neutrophils, PU.1, PU.1 binding variants, autoimmune and inflammatory diseases, autoimmune disease, enhancer-promoter, immune disease, myeloid master regulator PU.1, neutrophil, neutrophil enhancers, primary neutrophils, target enhancers
Author NameAffiliation
Stephen WattWellcome Sanger Institute
Stephen WattWellcome Sanger Institute
Louella VasquezWellcome Sanger Institute
Klaudia WalterWellcome Sanger Institute
Alice L MannWellcome Sanger Institute
Kousik KunduWellcome Sanger Institute
Kousik KunduSchool of Clinical Medicine, University of Cambridge
Lu ChenWellcome Sanger Institute
Lu ChenWest China Second University Hospital, Sichuan University
Lu ChenSchool of Clinical Medicine, University of Cambridge
Frances BurdenUniversity of Cambridge
Frances BurdenNational Health Service Blood and Transplant (NHSBT)
Samantha FarrowUniversity of Cambridge
Samantha FarrowNational Health Service Blood and Transplant (NHSBT)
David RichardsonEuropean Bioinformatics Institute
Paul FlicekEuropean Bioinformatics Institute
Paul FlicekEuropean Bioinformatics Institute
Laura ClarkeEuropean Bioinformatics Institute
Kate DownesUniversity of Cambridge
Kate DownesNational Health Service Blood and Transplant (NHSBT)
Tomi PastinenCenter for Pediatric Genomic Medicine
Mattia FrontiniUniversity of Cambridge
Mattia FrontiniInstitute of Biomedical & Clinical Science, College of Medicine and Health, University of Exeter Medical School
Mattia FrontiniBritish Heart Foundation Centre of Excellence, Addenbrooke's Hospital
Mattia FrontiniNational Health Service Blood and Transplant (NHSBT)
Nicole SoranzoWellcome Sanger Institute
Nicole SoranzoSchool of Clinical Medicine, University of Cambridge
Nicole SoranzoWellcome Sanger Institute
Nicole SoranzoSchool of Clinical Medicine, University of Cambridge
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