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Paper Title
EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer.
PubMed
Paper Journal Title
Oncogene
Paper Citation Count
71
Paper Publication Year
2018
Bio Mention
-, ADP, BRCA, BRCA-mutant breast cancer, BRCA-mutant breast cells, BRCA-mutant ovarian cancer, BRCA-mutated breast and ovarian cancers, EZH2, H3, PAR, PARP, PARP1, PARPi, PARPi-untreated cells, PARPis, PRC2 complex, alkylating DNA, breast cancer, breast cancer cells, cancer, cancer stem cell, enhancer of zeste homolog 2, lysine, poly (ADP-ribose), poly (ADP-ribose) polymerase, poly-ADP-ribose, untreated cells
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Author Name
Affiliation
Jun Yao
The University of Texas MD Anderson Cancer Center
Gabriel N Hortobagyi
The University of Texas MD Anderson Cancer Center
Mien-Chie Hung
The University of Texas MD Anderson Cancer Center
Mien-Chie Hung
Graduate Institute of Biomedical Sciences and Center for Molecular Medicine, China Medical University
Mien-Chie Hung
Asia University
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