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Paper Details

Aldosterone stimulates elastogenesis in cardiac fibroblasts via mineralocorticoid receptor-independent action involving the consecutive activation of Galpha13, c-Src, the insulin-like growth factor-I receptor, and phosphatidylinositol 3-kinase/Akt.
J Biol Chem
43
2009
Akt, Aldosterone, Galpha13, Galphai proteins, I receptor, IGF-IR, MR, aldosterone, c-Src, cardiac fibroblasts, collagen, elastin, heterotrimeric G protein, human, human cardiac fibroblasts, insulin-like growth factor-, insulin-like growth factor-I receptor, mineralocorticoid receptor, pertussis toxin, phosphatidylinositol, phosphatidylinositol 3-kinase, small, small interfering RNA
Author NameAffiliation
Severa BundaThe Hospital for Sick Children
Peter P LiuUniversity of Toronto, Canada Toronto General Hospital/University Health Network
Sara ArabToronto General Hospital/University Health Network
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Release 1.2