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Paper Details

Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation.
J Exp Clin Cancer Res
22
2019
Heart failure, K+, MYC, MYC overexpressing leukemia, MYC overexpressing leukemia cells, MYC protein, MYC target proteins, Na+, Na+/K+, Proscillaridin A, RNA, cancer, chromatin, heart failure, hematopoietic differentiation genes, histone, histone H3, histone acetylation, histone acetyltransferases, human, human leukemia and solid tumor cell lines, in, leukemia, leukemia and solid tumor, leukemia cells, leukemia stem cells, leukemic cells, lymphoid and myeloid stem cell populations, lysine, non, proscillaridin, proscillaridin A
Acetylation, Antineoplastic Agents, Cell Differentiation, Cell Line, Tumor, Cell Proliferation, Chromatin, Dose-Response Relationship, Drug, Epigenesis, Genetic, Gene Expression, Gene Expression Profiling, Genes, myc, Heart Failure, Histones, Humans, Leukemia, Lysine, Models, Biological, Proscillaridin, T-Lymphocytes
Author NameAffiliation
Elodie M Da CostaDepartement de pharmacologie et physiologie, Universite de Montreal
Elodie M Da CostaSainte-Justine University Hospital Research Center (7.17.)
Gregory ArmaosDepartement de pharmacologie et physiologie, Universite de Montreal
Gregory ArmaosSainte-Justine University Hospital Research Center (7.17.)
Gabrielle McInnesDepartement de pharmacologie et physiologie, Universite de Montreal
Gabrielle McInnesSainte-Justine University Hospital Research Center (7.17.)
Annie BeaudrySainte-Justine University Hospital Research Center (7.17.)
Ga??l Moquin-BeaudryDepartement de pharmacologie et physiologie, Universite de Montreal
Ga??l Moquin-BeaudrySainte-Justine University Hospital Research Center (7.17.)
Virginie Bertrand-LehouillierSainte-Justine University Hospital Research Center (7.17.)
Virginie Bertrand-LehouillierUniversite de Montreal
Maxime CaronSainte-Justine University Hospital Research Center (7.17.)
Chantal RicherSainte-Justine University Hospital Research Center (7.17.)
Pascal St-OngeSainte-Justine University Hospital Research Center (7.17.)
Jeffrey R JohnsonUniversity of California san francisco
Nevan J Krogan (CM4AI)University of California san francisco
Yuka SaiOttawa Institute of Systems Biology
Michael DowneyOttawa Institute of Systems Biology
Moutih RafeiDepartement de pharmacologie et physiologie, Universite de Montreal
Moutih RafeiUniversite de Montreal
Moutih RafeiMcGill University
Meaghan BoileauMcGill University
Kolja EppertMcGill University
Ema Flores-D??azInstitute of Research in Immunology and Cancer, Universite de Montreal
Andr?? HamanInstitute of Research in Immunology and Cancer, Universite de Montreal
Trang HoangDepartement de pharmacologie et physiologie, Universite de Montreal
Trang HoangInstitute of Research in Immunology and Cancer, Universite de Montreal
Daniel SinnettSainte-Justine University Hospital Research Center (7.17.)
Daniel SinnettUniversite de Montreal
Christian Beaus??jourDepartement de pharmacologie et physiologie, Universite de Montreal
Christian Beaus??jourSainte-Justine University Hospital Research Center (7.17.)
Serge McGrawSainte-Justine University Hospital Research Center (7.17.)
Serge McGrawUniversite de Montreal
Serge McGrawUniversite de Montreal
No??l J-M RaynalDepartement de pharmacologie et physiologie, Universite de Montreal
No??l J-M RaynalSainte-Justine University Hospital Research Center (7.17.)
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