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Paper Details

Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator.
J Biol Chem
6
2018
ATP, F508del, cystic fibrosis, dTTP, full-length F508del-hCFTR, hCFTR, hNBD1, human, human cystic fibrosis transmembrane conductance regulator, methyl, nucleotide, nucleotide-binding domain 1, nucleotides, remote site
Author NameAffiliation
Brent R StockwellColumbia University
Brent R StockwellColumbia University
Nikolay V DokholyanUniversity of North Carolina
John F Hunt
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Release 1.2