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Paper Details

A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density.
Cell Metab
23
2021
3q21, ADCY5, ADCY5 gene, SREBP1, adenylate, adenylate cyclase 5, adenylate cyclase 5 (ADCY5) intronic causal variant, adipocytes, bivariate risk locus, chromatin, fatty acid, genetic loci, hyperglycemia, osteoblast, osteoblasts, pleiotropic GWAS loci, regulatory variant, rs56371916, target gene, type 2 diabetes
Author NameAffiliation
Teresa FerreiraBig Data Institute, University of Oxford
David KarasikInstitute for Aging Research, Hebrew SeniorLife and Harvard Medical School, Bar-Ilan University
Manuel A RivasStanford University
Manuel A RivasStanford University
Jonathan K PritchardStanford University
Cecilia M LindgrenBroad Institute of MIT and Harvard, USA Big Data Institute, University of Oxford
Clifford J RosenCenter for Molecular Medicine, Maine Medical Center Research Institute
Eric S LanderBroad Institute of MIT and Harvard, Harvard Medical School
Eric S LanderBroad Institute of MIT and Harvard, Harvard Medical School
Douglas P KielInstitute for Aging Research, Hebrew SeniorLife and Harvard Medical School, Beth Israel Deaconess Medical Center, Harvard Medical School
Douglas P KielInstitute for Aging Research, Hebrew SeniorLife and Harvard Medical School, Beth Israel Deaconess Medical Center, Harvard Medical School
Melina ClaussnitzerBroad Institute of MIT and Harvard, Beth Israel Deaconess Medical Center, Harvard Medical School, USA University of Hohenheim, Institute of Nutritional Science
Melina ClaussnitzerBroad Institute of MIT and Harvard, Beth Israel Deaconess Medical Center, Harvard Medical School, USA University of Hohenheim, Institute of Nutritional Science
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