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Paper Details

Remdesivir for the Treatment of Covid-19 - Final Report.
N Engl J Med
4730
2020
Allergy, Covid, Patients, Remdesivir, coronavirus disease, lower respiratory tract infection, patients, remdesivir
Author NameAffiliation
Aneesh K MehtaFrom the National Institute of Allergy and Infectious Diseases, National Institutes of Health (J.H.B., and the Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences (T.H.B.), the Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, M.M.) - all in Maryland Emory University, Atlanta (A.K.M.) Montefiore Medical Center-Albert Einstein College of Medicine (B.S.Z.) and NYU Langone Health and NYC Health and Hospitals-Bellevue (K.D.), New York University of Nebraska Medical Center, M.G.K.) Massachusetts General Hospital, and University of Massachusetts Medical School, Worcester (R.W.F.) University of Washington, and Evergreen Health Medical Center, Kirkland (D.L.C.) - both in Washington University of California, Cedars-Sinai Medical Center, University of California, Foster City (A.O.) - all in California University of Minnesota (S.K.) and University of Minnesota School of Public Health and INSIGHT (J.D.N.), Minneapolis University of Texas Health San Antonio, University Health System, and Baylor College of Medicine, Houston (R.L.A.) Hospital Germans Trias i Pujol and irsiCaixa AIDS Research Institute, Spain (R.P.) University of Pennsylvania, Philadelphia (W.R.S.) Medical School, National and Kapodistrian University of Athens, Athens (G.T.) National Center for Infectious Diseases-Tan Tock Seng Hospital-Lee Kong Chian School of Medicine-Yong Loo Lin School of Medicine, Singapore (D.C.L.) the National Center for Global Health and Medicine Hospital, Tokyo (N.O.) Seoul National University Hospital, South Korea (M.O.) Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Amager Hvidovre Hospital-University of Copenhagen, and Rigshospitalet, Copenhagen (J.L.) - both in Denmark University Hospital of Cologne, Germany (G.F.) Vanderbilt University Medical Center, Nashville (C.B.C.) and University College London, MRC Clinical Trials Unit at UCL and INSIGHT
Aneesh K MehtaFrom the National Institute of Allergy and Infectious Diseases, National Institutes of Health (J.H.B., and the Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences (T.H.B.), the Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, M.M.) - all in Maryland Emory University, Atlanta (A.K.M.) Montefiore Medical Center-Albert Einstein College of Medicine (B.S.Z.) and NYU Langone Health and NYC Health and Hospitals-Bellevue (K.D.), New York University of Nebraska Medical Center, M.G.K.) Massachusetts General Hospital, and University of Massachusetts Medical School, Worcester (R.W.F.) University of Washington, and Evergreen Health Medical Center, Kirkland (D.L.C.) - both in Washington University of California, Cedars-Sinai Medical Center, University of California, Foster City (A.O.) - all in California University of Minnesota (S.K.) and University of Minnesota School of Public Health and INSIGHT (J.D.N.), Minneapolis University of Texas Health San Antonio, University Health System, and Baylor College of Medicine, Houston (R.L.A.) Hospital Germans Trias i Pujol and irsiCaixa AIDS Research Institute, Spain (R.P.) University of Pennsylvania, Philadelphia (W.R.S.) Medical School, National and Kapodistrian University of Athens, Athens (G.T.) National Center for Infectious Diseases-Tan Tock Seng Hospital-Lee Kong Chian School of Medicine-Yong Loo Lin School of Medicine, Singapore (D.C.L.) the National Center for Global Health and Medicine Hospital, Tokyo (N.O.) Seoul National University Hospital, South Korea (M.O.) Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Amager Hvidovre Hospital-University of Copenhagen, and Rigshospitalet, Copenhagen (J.L.) - both in Denmark University Hospital of Cologne, Germany (G.F.) Vanderbilt University Medical Center, Nashville (C.B.C.) and University College London, MRC Clinical Trials Unit at UCL and INSIGHT
Andre C KalilFrom the National Institute of Allergy and Infectious Diseases, National Institutes of Health (J.H.B., and the Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences (T.H.B.), the Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, M.M.) - all in Maryland Emory University, Atlanta (A.K.M.) Montefiore Medical Center-Albert Einstein College of Medicine (B.S.Z.) and NYU Langone Health and NYC Health and Hospitals-Bellevue (K.D.), New York University of Nebraska Medical Center, M.G.K.) Massachusetts General Hospital, and University of Massachusetts Medical School, Worcester (R.W.F.) University of Washington, and Evergreen Health Medical Center, Kirkland (D.L.C.) - both in Washington University of California, Cedars-Sinai Medical Center, University of California, Foster City (A.O.) - all in California University of Minnesota (S.K.) and University of Minnesota School of Public Health and INSIGHT (J.D.N.), Minneapolis University of Texas Health San Antonio, University Health System, and Baylor College of Medicine, Houston (R.L.A.) Hospital Germans Trias i Pujol and irsiCaixa AIDS Research Institute, Spain (R.P.) University of Pennsylvania, Philadelphia (W.R.S.) Medical School, National and Kapodistrian University of Athens, Athens (G.T.) National Center for Infectious Diseases-Tan Tock Seng Hospital-Lee Kong Chian School of Medicine-Yong Loo Lin School of Medicine, Singapore (D.C.L.) the National Center for Global Health and Medicine Hospital, Tokyo (N.O.) Seoul National University Hospital, South Korea (M.O.) Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Amager Hvidovre Hospital-University of Copenhagen, and Rigshospitalet, Copenhagen (J.L.) - both in Denmark University Hospital of Cologne, Germany (G.F.) Vanderbilt University Medical Center, Nashville (C.B.C.) and University College London, MRC Clinical Trials Unit at UCL and INSIGHT
Mark G KortepeterFrom the National Institute of Allergy and Infectious Diseases, National Institutes of Health (J.H.B., and the Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences (T.H.B.), the Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, M.M.) - all in Maryland Emory University, Atlanta (A.K.M.) Montefiore Medical Center-Albert Einstein College of Medicine (B.S.Z.) and NYU Langone Health and NYC Health and Hospitals-Bellevue (K.D.), New York University of Nebraska Medical Center, M.G.K.) Massachusetts General Hospital, and University of Massachusetts Medical School, Worcester (R.W.F.) University of Washington, and Evergreen Health Medical Center, Kirkland (D.L.C.) - both in Washington University of California, Cedars-Sinai Medical Center, University of California, Foster City (A.O.) - all in California University of Minnesota (S.K.) and University of Minnesota School of Public Health and INSIGHT (J.D.N.), Minneapolis University of Texas Health San Antonio, University Health System, and Baylor College of Medicine, Houston (R.L.A.) Hospital Germans Trias i Pujol and irsiCaixa AIDS Research Institute, Spain (R.P.) University of Pennsylvania, Philadelphia (W.R.S.) Medical School, National and Kapodistrian University of Athens, Athens (G.T.) National Center for Infectious Diseases-Tan Tock Seng Hospital-Lee Kong Chian School of Medicine-Yong Loo Lin School of Medicine, Singapore (D.C.L.) the National Center for Global Health and Medicine Hospital, Tokyo (N.O.) Seoul National University Hospital, South Korea (M.O.) Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Amager Hvidovre Hospital-University of Copenhagen, and Rigshospitalet, Copenhagen (J.L.) - both in Denmark University Hospital of Cologne, Germany (G.F.) Vanderbilt University Medical Center, Nashville (C.B.C.) and University College London, MRC Clinical Trials Unit at UCL and INSIGHT
Timothy H BurgessFrom the National Institute of Allergy and Infectious Diseases, National Institutes of Health (J.H.B., and the Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences (T.H.B.), the Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, M.M.) - all in Maryland Emory University, Atlanta (A.K.M.) Montefiore Medical Center-Albert Einstein College of Medicine (B.S.Z.) and NYU Langone Health and NYC Health and Hospitals-Bellevue (K.D.), New York University of Nebraska Medical Center, M.G.K.) Massachusetts General Hospital, and University of Massachusetts Medical School, Worcester (R.W.F.) University of Washington, and Evergreen Health Medical Center, Kirkland (D.L.C.) - both in Washington University of California, Cedars-Sinai Medical Center, University of California, Foster City (A.O.) - all in California University of Minnesota (S.K.) and University of Minnesota School of Public Health and INSIGHT (J.D.N.), Minneapolis University of Texas Health San Antonio, University Health System, and Baylor College of Medicine, Houston (R.L.A.) Hospital Germans Trias i Pujol and irsiCaixa AIDS Research Institute, Spain (R.P.) University of Pennsylvania, Philadelphia (W.R.S.) Medical School, National and Kapodistrian University of Athens, Athens (G.T.) National Center for Infectious Diseases-Tan Tock Seng Hospital-Lee Kong Chian School of Medicine-Yong Loo Lin School of Medicine, Singapore (D.C.L.) the National Center for Global Health and Medicine Hospital, Tokyo (N.O.) Seoul National University Hospital, South Korea (M.O.) Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Amager Hvidovre Hospital-University of Copenhagen, and Rigshospitalet, Copenhagen (J.L.) - both in Denmark University Hospital of Cologne, Germany (G.F.) Vanderbilt University Medical Center, Nashville (C.B.C.) and University College London, MRC Clinical Trials Unit at UCL and INSIGHT
Henry Clifford LaneFrom the National Institute of Allergy and Infectious Diseases, National Institutes of Health (J.H.B., and the Infectious Disease Clinical Research Program, Uniformed Services University of the Health Sciences (T.H.B.), the Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, M.M.) - all in Maryland Emory University, Atlanta (A.K.M.) Montefiore Medical Center-Albert Einstein College of Medicine (B.S.Z.) and NYU Langone Health and NYC Health and Hospitals-Bellevue (K.D.), New York University of Nebraska Medical Center, M.G.K.) Massachusetts General Hospital, and University of Massachusetts Medical School, Worcester (R.W.F.) University of Washington, and Evergreen Health Medical Center, Kirkland (D.L.C.) - both in Washington University of California, Cedars-Sinai Medical Center, University of California, Foster City (A.O.) - all in California University of Minnesota (S.K.) and University of Minnesota School of Public Health and INSIGHT (J.D.N.), Minneapolis University of Texas Health San Antonio, University Health System, and Baylor College of Medicine, Houston (R.L.A.) Hospital Germans Trias i Pujol and irsiCaixa AIDS Research Institute, Spain (R.P.) University of Pennsylvania, Philadelphia (W.R.S.) Medical School, National and Kapodistrian University of Athens, Athens (G.T.) National Center for Infectious Diseases-Tan Tock Seng Hospital-Lee Kong Chian School of Medicine-Yong Loo Lin School of Medicine, Singapore (D.C.L.) the National Center for Global Health and Medicine Hospital, Tokyo (N.O.) Seoul National University Hospital, South Korea (M.O.) Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Amager Hvidovre Hospital-University of Copenhagen, and Rigshospitalet, Copenhagen (J.L.) - both in Denmark University Hospital of Cologne, Germany (G.F.) Vanderbilt University Medical Center, Nashville (C.B.C.) and University College London, MRC Clinical Trials Unit at UCL and INSIGHT
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Datasets

ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link
ClinicalTrials.govClinicalTrials.gov, a registry and results database of of privately and publicly funded clinical studies conducted around the world, is operated by the U.S. National Library of Medicine (NLM). Structured study information is provided, voluntarily or to meet legal and policy requirements, by the sponsor or investigator responsible for the research. NLM does not verify the scientific validity or relevance of the submitted information beyond a limited quality control review for apparent errors, deficiencies, or inconsistencies.Link