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Paper Details

Partial RAG deficiency in humans induces dysregulated peripheral lymphocyte development and humoral tolerance defect with accumulation of T-bet<sup>+</sup> B cells.
Nat Immunol
17
2022
B, B cell, B cell dysregulation, B cell fate, B cell receptor, B cell repertoire, B cell-activating factor, Partial RAG deficiency, RAG, RAG deficiency, RAG1, RAG2, T-, T-bet B cells, humans, humoral tolerance defect, immune dysregulation, pRD, recombination-activating genes (RAG) 1 and 2, repertoires, self-reactive clones
Author NameAffiliation
Joseph D HernandezStanford University
Stefania PittalugaCenter for Cancer Research, National Cancer Institute, National Institutes of Health
Stefania PittalugaCenter for Cancer Research, National Cancer Institute, National Institutes of Health
Manish J ButteDepartment of Pediatrics and Jeffrey Modell Diagnostic and Research Center, University of California los angeles
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Release 1.2