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Paper Details

Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells.
Proc Natl Acad Sci U S A
61
2014
-, -Ms, ABL, DCs, DCs-Ms, HG-9-91-01, IL-, IL-1, IL-10, IL-6, Ms, Myeloid cells, SIK, SIKs, SRC-family, TNF-,, anti-inflammatory CD11c(+) CX3CR1(hi) cells, bosutinib, colitis, dasatinib, dendritic cells, human, human DCs, macrophages, man, mouse, murine, murine bone-marrow-derived, myeloid cells, salt-inducible kinases, saracatinib, yeast
Author NameAffiliation
Thomas B SundbergCenter for the Science of Therapeutics, Broad Institute
Bernard KhorCenter for Computational and Integrative Biology, Massachusetts General Hospital
Vlado Dan????kCenter for the Science of Therapeutics, Broad Institute
Nathanael S GrayHarvard Medical School, Dana-Farber Cancer Institute
Nathanael S GrayHarvard Medical School, Dana-Farber Cancer Institute
Stuart L SchreiberCenter for the Science of Therapeutics, Broad Institute, Harvard University, MA 02138 Howard Hughes Medical Institute, MA 02142 xavier@molbio.mgh.harvard.edu ashamji@broadinstitute.org.
Stuart L SchreiberCenter for the Science of Therapeutics, Broad Institute, Harvard University, MA 02138 Howard Hughes Medical Institute, MA 02142 xavier@molbio.mgh.harvard.edu ashamji@broadinstitute.org.
Ramnik J XavierGastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Broad Institute, MA 02142 and Center for Computational and Integrative Biology, MA 02114 xavier@molbio.mgh.harvard.edu ashamji@broadinstitute.org.
Ramnik J XavierGastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Broad Institute, MA 02142 and Center for Computational and Integrative Biology, MA 02114 xavier@molbio.mgh.harvard.edu ashamji@broadinstitute.org.
Alykhan F ShamjiCenter for the Science of Therapeutics, Broad Institute, MA 02142 xavier@molbio.mgh.harvard.edu ashamji@broadinstitute.org.
Alykhan F ShamjiCenter for the Science of Therapeutics, Broad Institute, MA 02142 xavier@molbio.mgh.harvard.edu ashamji@broadinstitute.org.
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