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Paper Details

Velcrin-induced selective cleavage of tRNA<sup>Leu</sup>(TAA) by SLFN12 causes cancer cell death.
Nat Chem Biol
9
2023
Leu, Leu-TTA codons, PDE3A, SLFN12, SLFN12 RNase, Schlafen family member 12, Velcrin, cancer, cancer cell, cancer cells, phosphodiesterase 3A, sensitive cells, tRNA(TAA), velcrin
Author NameAffiliation
Xiaoyun WuBroad Institute
Xiaoyun Wu
Marcus T??tzlBroad Institute
Marcus T??tzlChildren's Cancer Research Institute
Matthew G ReesBroad Institute
Andrew D CherniackBroad Institute
Andrew D CherniackDana-Farber Cancer Institute
Andrew D CherniackBroad Institute
Andrew D CherniackDana-Farber Cancer Institute
Matthew MeyersonBroad Institute
Matthew MeyersonDana-Farber Cancer Institute
Matthew MeyersonBroad Institute
Matthew MeyersonDana-Farber Cancer Institute
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