Skip to Main Content

Paper Details

TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.
Cell
63
2021
COVID-19, SARS, SARS-CoV, SARS-CoV-2, TOP1, TPT, coronavirus disease, humans, inflammation, mouse, severe, severe acute respiratory syndrome coronavirus, topoisomerase 1, topotecan
Author NameAffiliation
Jessica Sook Yuin HoIcahn School of Medicine at Mount Sinai
Laura CampisiIcahn School of Medicine at Mount Sinai
Soner YildizIcahn School of Medicine at Mount Sinai
David A MeekinsCollege of Veterinary Medicine, Kansas State University
Raveen RathnasingheIcahn School of Medicine at Mount Sinai
Simin ZhengIcahn School of Medicine at Mount Sinai
Nan ZhaoIcahn School of Medicine at Mount Sinai
Nan ZhaoIcahn School of Medicine at Mount Sinai
Kris M WhiteIcahn School of Medicine at Mount Sinai
Teresa AydilloIcahn School of Medicine at Mount Sinai
Ernesto GuccioneTisch Cancer Institute, Department of Oncological Sciences and Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Robert SebraIcahn School of Medicine at Mount Sinai, USA Icahn Institute of Genomics and Multiscale Biology, USA Black Family Stem Cell Institute
Robert SebraIcahn School of Medicine at Mount Sinai, USA Icahn Institute of Genomics and Multiscale Biology, USA Black Family Stem Cell Institute
David A KaufmanNYU School of Medicine
Minji ByunClinical Immunology, Icahn School of Medicine at Mount Sinai
Randy A AlbrechtIcahn School of Medicine at Mount Sinai, USA Global Health and Emerging Pathogens Institute
Michael SchotsaertIcahn School of Medicine at Mount Sinai, USA Global Health and Emerging Pathogens Institute
Adolfo Garc??a-SastreIcahn School of Medicine at Mount Sinai, USA Tisch Cancer Institute, Department of Oncological Sciences and Department of Pharmacological Sciences, USA Global Health and Emerging Pathogens Institute
Sumit K ChandaSanford Burnham Prebys Medical Discovery Institute
Benjamin R tenOeverIcahn School of Medicine at Mount Sinai, USA Global Health and Emerging Pathogens Institute, USA Virus Engineering Center for Therapeutics and Research
Matthew T WeirauchCenter for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, College of Medicine
Matthew T WeirauchCenter for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, College of Medicine
Sven HeinzUniversity of California
Sven HeinzUniversity of California
Christopher BennerUniversity of California
Christopher BennerUniversity of California
Juergen A RichtKansas State University, College of Veterinary Medicine
Ivan MarazziIcahn School of Medicine at Mount Sinai, USA Global Health and Emerging Pathogens Institute
  • 1 - 28

Datasets