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Paper Details

Simultaneous inhibition of Sirtuin 3 and cholesterol homeostasis targets acute myeloid leukemia stem cells by perturbing fatty acid β-oxidation and inducing lipotoxicity.
Haematologica
6
2023
AML, ATP, BCL-2, LSC, SIRT3, Sirtuin 3, YC8-02, acute myeloid leukemia, acute myeloid leukemia stem cells, cancer, cancer models, cholesterol, disease, disease-initiating leukemia stem cells, fatty acid, human, human LSC, human hematopoietic stem and progenitor cell, lipotoxicity, patients, primary human LSC, primitive AML cells, venetoclax
Author NameAffiliation
Rachel Culp-HillUniversity of Colorado Anschutz Medical Campus
Julie A ReiszUniversity of Colorado Anschutz Medical Campus
Fabia GamboniUniversity of Colorado Anschutz Medical Campus
John E DickPrincess Margaret Cancer Centre, University Health Network
Ari MelnickWeill Cornell Medical College
Brian RaughtUniversity of Toronto, Canada Princess Margaret Cancer Centre, University Health Network
Angelo D'AlessandroUniversity of Colorado Anschutz Medical Campus
Angelo D'AlessandroUniversity of Colorado Anschutz Medical Campus
Courtney L JonesUniversity of Toronto, Canada Princess Margaret Cancer Centre, University Health Network
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