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Paper Details

Forced dimerization increases the activity of οEGFR/EGFRvIII and enhances its oncogenicity.
Mol Cancer Res
17
2011
Delta epidermal growth factor receptor, EGFR, EGFRvIII, FK506, FKBP12 protein, chimeric EGFR, glioblastoma, oncogene, tumor, wild
Animals, Cell Line, Tumor, ErbB Receptors, Gene Expression Regulation, Neoplastic, Glioma, Humans, Mice, Mice, Nude, Phosphorylation, Protein Multimerization, Protein Structure, Tertiary, Recombinant Fusion Proteins, Sequence Deletion, Signal Transduction, Tacrolimus Binding Protein 1A, Transcriptional Activation, Wound Healing
Author NameAffiliation
YeoHyeon HwangUniversity of Texas MD Anderson Cancer Center
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Release 1.2