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Paper Details

Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.
Cell
152
2019
-, G protein-coupled receptor, Gs, Human, MC4R, MC4R Variants, MC4R variants, Obesity, arrestin, cardiometabolic diseases, coronary artery disease, cyclic adenosine-monophosphate, melanocortin 4 receptor, mitogen-activated protein kinase, obesity, people, type 2 diabetes
Author NameAffiliation
Luca A LottaUniversity of Cambridge MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital
Stephen J SharpUniversity of Cambridge MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital
Jian'an LuanUniversity of Cambridge MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital
Nicola D KerrisonUniversity of Cambridge MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital
Eleanor WheelerUniversity of Cambridge MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital
John R B PerryUniversity of Cambridge MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital
Claudia LangenbergUniversity of Cambridge MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital
Nicholas J WarehamUniversity of Cambridge MRC Epidemiology Unit, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital
Ismaa Sadaf FarooqiUniversity of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital
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Release 1.2