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Paper Details

Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis.
Sci Rep
6
2021
AZD3355, ERK kinases, GABA, GABA-B receptor, Lesogaberan, MAP and, Myc, NASH, Non-alcoholic steatohepatitis, PCLS, SMA, TNF- mRNAs, collagen11, collagen11, SMA and TNF- mRNAs, esophageal reflux, human, human stellate cells, mouse, murine, non-alcoholic steatohepatitis, obeticholic acid, patients, profibrogenic gene, profibrotic gene, tumor
Author NameAffiliation
Ben ReadheadIcahn School of Medicine at Mount Sinai
Ben ReadheadArizona State University-Banner Neurodegenerative Disease Research Center
Joel T DudleyIcahn School of Medicine at Mount Sinai
Joel T DudleyIcahn School of Medicine at Mount Sinai
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Release 1.2